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pseudobulbar palsy : ウィキペディア英語版
pseudobulbar palsy

Pseudobulbar palsy is a medical condition characterised by the inability to control facial movements (such as chewing and speaking) and caused by a variety of neurological disorders. Patients experience difficulty chewing and swallowing, have increased reflexes and spasticity in tongue and the bulbar region, and demonstrate slurred speech (which is often the initial presentation of the disorder), sometimes also demonstrating uncontrolled emotional outbursts.
The condition is usually caused by the damage (bilateral degeneration) to the neurons of the brain stem, specifically to the corticobulbar tract (upper motor neuron tract to cranial nerve motor nuclei).
== Causes ==

Pseudobulbar palsy is the result of damage of motor fibers traveling from the cerebral cortex to the lower brain stem. This damage might arise in the course of a variety of neurological conditions that involve demyelination and bilateral corticobulbar lesions. Examples include:
* Vascular causes: bilateral hemisphere infarction, CADASIL syndrome
* Progressive supranuclear palsy
* Amyotrophic lateral sclerosis
* Parkinson's disease and related multiple system atrophy
* Various motor neuron diseases, especially those involving demyelination
* Multiple sclerosis and other inflammatory disorders
* High brain stem tumors
* Metabolic causes: osmotic demyelination syndrome〔]〕
* Neurological involvement in Behçet's disease
* Brain trauma

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「pseudobulbar palsy」の詳細全文を読む



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